Description

(7S-Cis)-9-Acetyl-7-((3-Amino-2,3,6-Trideoxy-β-L-Lyxo-Hexopyranosyl)Oxy)-7,8,9,10-Tetrahydro-6,9,11-Trihydroxy-5,12-Naphthacenedione is a structurally complex anthracycline derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and study of novel chemotherapeutic agents, particularly within the anthracycline antibiotic class. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on oncology drug discovery, process development, and analytical method validation.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for novel anthracycline-based anticancer drugs.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC/QA) of related active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR), mechanism of action, and metabolism of anthracycline compounds.
• Process Chemistry: Serves as a precursor or intermediate in scaling up the production of specialized therapeutic agents under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and oncology.

Basic Information

Product Name	(7S-Cis)-9-Acetyl-7-((3-Amino-2,3,6-Trideoxy-β-L-Lyxo-Hexopyranosyl)Oxy)-7,8,9,10-Tetrahydro-6,9,11-Trihydroxy-5,12-Naphthacenedione
CAS No.	58957-93-0
Molecular Formula	C25H27NO10
Molecular Weight	501.48 g/mol
Synonyms	9-Acetyl-7-((3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione; (7S-cis)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxynaphthacene-5,12-dione; Aclacinomycin A aglycone derivative; Anthracycline intermediate; 7-Deoxyaklavinone derivative; 2,3,6-Trideoxy-3-amino-α-L-lyxo-hexopyranoside derivative; 58957-93-0
EINECS	Contact for details

Quality Control

Our (7S-Cis)-9-Acetyl-7-((3-Amino-2,3,6-Trideoxy-β-L-Lyxo-Hexopyranosyl)Oxy)-7,8,9,10-Tetrahydro-6,9,11-Trihydroxy-5,12-Naphthacenedione is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR, MS), and residual solvent analysis, to ensure it meets the stringent requirements for research and pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under dry, inert conditions at a controlled room temperature (15-25°C). For long-term stability, consider storage at 2-8°C. Keep the container tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.