Description

(8S,10S)-10-((3-Amino-2,3-Dideoxy-α-L-Arabinohexopyranosyl)Oxy)-7, 8,9,10-Tetrahydro-6,8,11-Trihydroxy-8-(Hydroxyacetyl)-1-Methoxy-5,12-Naphthacenedione is a structurally complex anthracycline derivative, a class of compounds renowned for their potent biological activity. This high-purity chemical intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology drug discovery and the development of targeted antibiotic therapies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel anthracycline-based chemotherapeutic agents.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action against various cancer cell lines.
• Antibiotic Development: Acts as a precursor in the research and development of next-generation antibiotics targeting resistant bacterial strains.
• Bioconjugation Studies: Utilized in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems due to its reactive functional groups.
• Structure-Activity Relationship (SAR) Research: Essential for medicinal chemistry programs aiming to modify the anthracycline scaffold to improve efficacy and reduce toxicity.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.

Basic Information

Product Name	(8S,10S)-10-((3-Amino-2,3-Dideoxy-α-L-Arabinohexopyranosyl)Oxy)-7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-8-(Hydroxyacetyl)-1-Methoxy-5,12-Naphthacenedione
CAS No.	58928-62-4
Molecular Formula	C₂₇H₃₀NO₁₂
Molecular Weight	560.53 g/mol
Synonyms	3'-Amino-3'-deoxy-α-L-daunosaminyl daunorubicin; 3'-Amino-3'-deoxy-α-L-daunosaminyldaunorubicin; 3'-Amino-3'-deoxy-α-L-daunosaminyl-daunomycin; Daunorubicin, 3'-amino-3'-deoxy-α-L-daunosaminyl-; 3'-Amino-3'-deoxy-α-L-daunosaminyl-daunorubicin; 3'-Amino-3'-deoxy-α-L-daunosaminyl-13-dihydrodaunomycin; A derivative of Daunorubicin
EINECS	Contact for details

Quality Control

Our (8S,10S)-10-((3-Amino-2,3-Dideoxy-α-L-Arabinohexopyranosyl)Oxy)-7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-8-(Hydroxyacetyl)-1-Methoxy-5,12-Naphthacenedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing purity, related substances, and other critical parameters are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.