Description

1-[5-(Fluoromethyl)Phenyl]-3-Hydroxy-2-Pyrazoline is a specialized fluorinated pyrazoline derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the fluoromethyl group can significantly influence biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate this unique fluorinated scaffold into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine moiety enhances lipophilicity and target binding.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex fluorinated heterocycles and specialty chemicals for material science applications.
• Biochemical Probe Development: Utilized in medicinal chemistry to study structure-activity relationships (SAR) due to its distinct fluorinated aromatic system.
• Academic & Industrial R&D: A valuable compound for methodological research in fluorination chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	1-[5-(Fluoromethyl)Phenyl]-3-Hydroxy-2-Pyrazoline
CAS No.	58773-10-7
Molecular Formula	C10H11FN2O
Molecular Weight	194.21 g/mol
Synonyms	3-Hydroxy-1-[5-(fluoromethyl)phenyl]-2-pyrazoline; 1-(5-Fluoromethylphenyl)-3-hydroxy-2-pyrazoline; 5-(Fluoromethyl)phenyl-3-hydroxypyrazoline; 58773-10-7; 1H-Pyrazol-3-ol, 2,5-dihydro-1-[5-(fluoromethyl)phenyl]-; Fluoromethylphenylhydroxypyrazoline
EINECS	Contact for details

Quality Control

Our 1-[5-(Fluoromethyl)Phenyl]-3-Hydroxy-2-Pyrazoline is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and impurity profile is provided with every shipment to guarantee reliable performance and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.