Description

9-Fluoro-11Beta,17-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-[(9E,12E)-Octadeca-9,12-Dienoate] CAS NO 58769-04-3 is a high-purity, synthetic corticosteroid derivative, specifically a linoleate ester prodrug. This compound is valued for its enhanced lipophilicity and targeted delivery potential in advanced pharmaceutical research and development. It is primarily utilized by R&D scientists and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel anti-inflammatory and immunosuppressive therapies.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of potent topical and systemic corticosteroid drugs.
• Prodrug Development: Serves as a model prodrug in research aimed at improving drug bioavailability, skin penetration, or localized delivery due to its esterified structure.
• Anti-inflammatory Agent Research: Used in preclinical studies to investigate mechanisms of action and efficacy of fluorinated corticosteroids.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related steroid APIs.
• Biochemical Research: A tool compound for studying glucocorticoid receptor interactions and metabolic pathways in experimental pharmacology.

Basic Information

Product Name	9-Fluoro-11Beta,17-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-[(9E,12E)-Octadeca-9,12-Dienoate]
CAS No.	58769-04-3
Molecular Formula	C40H59FO6
Molecular Weight	654.89 g/mol
Synonyms	Fluocortin Butyl Linoleate; 9α-Fluoro-11β,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-linoleate; Fluocortin-21-linoleate; 16α-Methyl-9α-fluoro-δ1-hydrocortisone-21-linoleate; Fluocortin Linoleate Ester; (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl (9E,12E)-9,12-octadecadienoate
EINECS	Contact for details

Quality Control

Our 9-Fluoro-11Beta,17-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-[(9E,12E)-Octadeca-9,12-Dienoate] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.