Description

Penirolol CAS NO 58503-83-6 is a high-purity pharmaceutical intermediate and research chemical belonging to the class of β-adrenergic blocking agents. This compound is critical for the development and synthesis of active pharmaceutical ingredients (APIs) targeting cardiovascular conditions. It is primarily utilized by pharmaceutical manufacturers and advanced research institutions engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of β-blocker APIs for hypertension and angina treatment.
• Research & Development: Used in preclinical and clinical studies to investigate cardiovascular pharmacology and drug mechanisms.
• Reference Standard: Serves as an analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for commercial drug manufacturing.
• Academic Research: Utilized in university and institutional labs for studying adrenergic receptor interactions and structure-activity relationships.

Basic Information

Item	Details
Product Name	Penirolol
CAS No.	58503-83-6
Molecular Formula	C16H25NO3
Molecular Weight	279.38 g/mol
Synonyms	Penirolol; (±)-Penirolol; 1-(tert-Butylamino)-3-[2-(cyclopentyloxy)phenoxy]-2-propanol; 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[2-(cyclopentyloxy)phenoxy]-; Penirolol [INN]; BRN 2933977; UNII-7V8A4U7985; (RS)-Penirolol
EINECS	Contact for details

Quality Control

Our Penirolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.