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2-Amino-3-Trifluoromethylbenzonitrile CAS NO 58458-14-3


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CAS No.:58458-14-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Amino-3-Trifluoromethylbenzonitrile is a high-value, multi-functional aromatic nitrile building block featuring both an amino and a trifluoromethyl group. This unique structure makes it a critical intermediate for synthesizing advanced molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development teams for constructing complex heterocycles and active ingredients.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors, receptor antagonists, and other biologically active compounds.
  • Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and pesticides where the trifluoromethyl group enhances lipophilicity and metabolic stability.
  • Material Science: Used in the research and production of specialty polymers, liquid crystals, and advanced organic electronic materials.
  • Chemical Research & Development: Serves as a versatile starting material for constructing complex heterocyclic frameworks like quinazolines, benzimidazoles, and other nitrogen-containing systems.
  • Dye & Pigment Industry: Intermediate for synthesizing specialized dyes and pigments with unique color fastness and stability properties.

Basic Information

Product Name 2-Amino-3-Trifluoromethylbenzonitrile
CAS No. 58458-14-3
Molecular Formula C8H5F3N2
Molecular Weight 186.14 g/mol
Synonyms 2-Amino-3-(trifluoromethyl)benzonitrile; 3-Trifluoromethyl-2-aminobenzonitrile; 2-Cyano-6-(trifluoromethyl)aniline; Benzonitrile, 2-amino-3-(trifluoromethyl)-; 2-Amino-alpha,alpha,α-trifluoro-m-toluonitrile
EINECS Contact for details

Quality Control

Our 2-Amino-3-Trifluoromethylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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