Description

2-Amino-6-(Trifluoromethyl)Benzonitrile is a high-value, multi-functional aromatic intermediate featuring both an amino and a nitrile group on a trifluoromethyl-substituted benzene ring. This unique structure makes it a critical building block for synthesizing advanced molecules with enhanced biological activity and physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Chemistry: Acts as an intermediate for synthesizing complex dyes and organic pigments with specific light-fastness and color properties.
• Cross-Coupling Reactions: The amino and cyano groups provide handles for palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) to construct complex biaryl systems.

Basic Information

Product Name	2-Amino-6-(Trifluoromethyl)Benzonitrile
CAS No.	58458-11-0
Molecular Formula	C8H5F3N2
Molecular Weight	186.14 g/mol
Synonyms	2-Amino-α,α,α-trifluoro-p-tolunitrile; 6-Amino-2-(trifluoromethyl)benzonitrile; 2-Cyano-3-(trifluoromethyl)aniline; 2-Amino-6-trifluoromethylbenzonitrile; Benzonitrile, 2-amino-6-(trifluoromethyl)-; 3-Amino-4-cyano-benzotrifluoride
EINECS	Contact for details

Quality Control

Our 2-Amino-6-(Trifluoromethyl)Benzonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.