Description

Bucumolol is a potent β-adrenergic receptor antagonist (β-blocker) with the CAS registry number 58409-59-9. This compound is of significant interest in pharmaceutical research and development for its potential cardiovascular applications. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, pharmacological studies, and analytical method development.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of β-blocker medications.
• Biochemical Research: Used as a reference standard or active compound in studies of adrenergic receptor function and signal transduction pathways.
• Analytical Standard: Serves as a high-purity standard for quality control (QC) and assurance (QA) in HPLC, LC-MS, and other analytical methods.
• Preclinical Studies: Employed in in vitro and in vivo models to investigate cardiovascular effects and pharmacokinetics.
• Chemical Reference Material: Used for spectroscopic calibration (NMR, IR) and method validation in analytical laboratories.

Basic Information

Product Name	Bucumolol
CAS No.	58409-59-9
Molecular Formula	C18H30N2O4
Molecular Weight	338.45 g/mol
Synonyms	1-(tert-Butylamino)-3-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methoxy]propan-2-ol; (±)-Bucumolol; Y-6124; Bucumolol Hydrochloride (salt form); 2-Propanol, 1-[(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolyl)methoxy]-3-[(1,1-dimethylethyl)amino]-; 3,4-Dihydro-6,7-dimethoxy-2-[[2-hydroxy-3-[(1,1-dimethylethyl)amino]propoxy]methyl]-1(2H)-isoquinolinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our Bucumolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.