Description

(Z)-3-[3-(Trifluoromethyl)Phenyl]Acrylonitrile is a high-value, fluorinated organic intermediate characterized by its acrylonitrile moiety attached to a trifluoromethylphenyl group. This compound is a critical building block in advanced organic synthesis, prized for its ability to introduce both a reactive double bond and a lipophilic, electron-withdrawing trifluoromethyl group into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Key intermediate in the synthesis of pharmaceutical candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Building block for advanced agrochemicals, including herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Precursor in materials science for the development of specialty polymers and liquid crystal compounds.
• Used in organic light-emitting diode (OLED) research as an electron-transport material component.
• Valuable reagent in academic and industrial research for studying structure-activity relationships (SAR) and cycloaddition reactions.
• Intermediate for synthesizing ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	(Z)-3-[3-(Trifluoromethyl)Phenyl]Acrylonitrile
CAS No.	58177-61-0
Molecular Formula	C10H6F3N
Molecular Weight	197.16 g/mol
Synonyms	(Z)-3-[3-(Trifluoromethyl)phenyl]-2-propenenitrile; (Z)-3-(3-Trifluoromethylphenyl)acrylonitrile; (Z)-3-(α,α,α-Trifluoro-m-tolyl)acrylonitrile; (Z)-3-(m-Trifluoromethylphenyl)acrylonitrile; (Z)-3-(3-(Trifluoromethyl)phenyl)prop-2-enenitrile; (Z)-3-(3-CF3-C6H4)-acrylonitrile; (Z)-Isomer of 3-(3-Trifluoromethylphenyl)acrylonitrile
EINECS	Contact for details

Quality Control

Our (Z)-3-[3-(Trifluoromethyl)Phenyl]Acrylonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0% (Area %)
Isomeric Purity (Z-Isomer)	≥ 99.0%
Melting Point	Contact for details
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.