Description

3-(4-Succinoylaminobutylamino)Propylaminobleomycin is a chemically modified derivative of the potent glycopeptide antibiotic bleomycin, designed to enhance its therapeutic profile. This compound is of significant interest for its potential to improve targeting and reduce systemic toxicity in oncological applications. It is primarily utilized by research institutions and pharmaceutical developers focused on advanced cancer therapeutics and drug delivery systems.

Application

• Anticancer Drug Development: Serves as a key intermediate or active component in the research and synthesis of novel chemotherapeutic agents.
• Targeted Therapy Conjugates: Used to create antibody-drug conjugates (ADCs) or other ligand-directed prodrugs for site-specific cancer treatment.
• Mechanism of Action Studies: Employed in biochemical and pharmacological research to investigate DNA cleavage mechanisms and cellular uptake pathways.
• Pharmaceutical Intermediate: Acts as a critical building block in the multi-step synthesis of complex bleomycin analogs with modified properties.
• Bioconjugation Research: Utilized in studies exploring the covalent attachment of therapeutic payloads to carriers like polymers or nanoparticles.

Basic Information

Product Name	3-(4-Succinoylaminobutylamino)Propylaminobleomycin
CAS No.	58071-33-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bleomycin derivative, 3-(4-Succinoylaminobutylamino)propylaminobleomycin; Bleomycin A2, 3-[4-[(3-carboxy-1-oxopropyl)amino]butylamino]propylamino-; N-Succinoyl-4-aminobutyl-3-aminopropylaminobleomycin; Propylaminobleomycin succinamide derivative
EINECS	Contact for details

Quality Control

Our 3-(4-Succinoylaminobutylamino)Propylaminobleomycin is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment and sealed immediately after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.