Description

Methanesulfonamide, n-(3-Cyanophenyl)-1,1,1-Trifluoro- is a specialized trifluoromethylated sulfonamide derivative, a high-value building block prized for its unique electronic and steric properties. This compound is critical for researchers and manufacturers developing advanced materials and active pharmaceutical ingredients (APIs) that require enhanced metabolic stability and lipophilicity. It serves as a key intermediate for agrochemicals, pharmaceutical candidates, and specialty polymers targeting global innovation-driven industries.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of novel drug candidates, particularly in kinase inhibitors and anti-inflammatory agents, where the trifluoromethyl group improves bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging its chemical stability and biological activity.
• Material Science: Serves as a monomer or functional additive in the synthesis of specialty polymers, coatings, and liquid crystals with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and as a precursor for more complex sulfonamide-based structures in fine chemical manufacturing.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry R&D in academic and industrial laboratories.

Basic Information

Product Name	Methanesulfonamide, n-(3-Cyanophenyl)-1,1,1-Trifluoro-
CAS No.	57946-16-4
Molecular Formula	C9H5F3N2O2S
Molecular Weight	262.21 g/mol
Synonyms	N-(3-Cyanophenyl)-1,1,1-trifluoromethanesulfonamide; 3-[(Trifluoromethyl)sulfonyl]aminobenzonitrile; 1,1,1-Trifluoro-N-(3-cyanophenyl)methanesulfonamide; 3-(Trifluoromethanesulfonamido)benzonitrile; α,α,α-Trifluoro-N-(3-cyanophenyl)methanesulfonamide; 3-Cyano-N-(trifluoromethylsulfonyl)aniline; Benzonitrile, 3-[(trifluoromethyl)sulfonyl]amino]-
EINECS	Contact for details

Quality Control

Our Methanesulfonamide, n-(3-Cyanophenyl)-1,1,1-Trifluoro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.