Description

(-)-Corynoxidine CAS NO 57906-85-1 is a specific stereoisomer of the oxindole alkaloid corynoxidine, known for its distinct biological profile. This compound is of significant interest in pharmaceutical and biochemical research due to its potential as a modulator of dopaminergic and serotonergic pathways. It serves as a critical reference standard and intermediate for researchers in neuropharmacology, natural product chemistry, and drug discovery.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of corynoxidine content in herbal extracts and finished products.
• Neuropharmacological Research: Investigated for its activity on neurotransmitter systems, particularly as a potential agent for studying Parkinson's disease and related neurological disorders.
• Natural Product Isolation & Synthesis: Acts as a key chiral building block or target molecule in the total synthesis of complex indole alkaloids.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) campaigns to identify new compounds with similar or enhanced biological activity.
• Academic & Institutional Research: Utilized in universities and research institutes for studies on alkaloid biosynthesis, structure-activity relationships (SAR), and medicinal chemistry.

Basic Information

Product Name	(-)-Corynoxidine
CAS No.	57906-85-1
Molecular Formula	C₂₁H₂₄N₂O₄
Molecular Weight	368.43 g/mol
Synonyms	Corynoxidine; (3S,15R,19E)-Corynoxidine; 19,20-Didehydro-10,17-dimethoxy-4-methyl-16-oxa-4-azayohimban-3-ol; Corynoxidine B; (-)-Corynoxidine; (3S,15R,19E)-3,17-Dihydroxy-10,16-dimethoxy-4-methyl-19,20-didehydroyohimban-16-ium-17-olate
EINECS	Contact for details

Quality Control

Our (-)-Corynoxidine is produced and handled under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.