Description

Quinine Hydrochloride Dihydrate is the dihydrate salt form of the natural alkaloid quinine, widely recognized for its distinct pharmacological properties. This high-purity compound is essential for applications demanding precise chemical structure and consistent bioactivity. It serves as a critical reference standard and active ingredient for the pharmaceutical, analytical, and life science research industries.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments and the quantification of quinine in drug formulations and compliance testing.
• Active Pharmaceutical Ingredient (API): Employed in the manufacture of antimalarial medications and other therapeutic agents.
• Biochemical Research: Serves as a key reagent and tool compound in pharmacological studies, particularly for investigating ion channel function and muscle physiology.
• Analytical Chemistry: Utilized as a standard in High-Performance Liquid Chromatography (HPLC) and other chromatographic methods for method development and validation.
• Bittering Agent: Applied in the food and beverage industry as a flavoring agent, most notably in tonic water.
• Laboratory Reagent: Used in various chemical syntheses and as a starting material for derivative preparation in organic chemistry.

Basic Information

Product Name	Quinine Hydrochloride Dihydrate
CAS No.	6119-47-7
Molecular Formula	C20H24N2O2 • 2HCl • 2H2O
Molecular Weight	396.90 g/mol (anhydrous salt basis)
Synonyms	Quinine Dihydrochloride Dihydrate; Quinine HCl Dihydrate; (8S,9R)-6'-Methoxycinchonan-9-ol Dihydrochloride Dihydrate; Cinchonan-9-ol, 6'-methoxy-, (8α,9R)-, dihydrochloride, dihydrate; NSC 199944; Quinine Hydrochloride (Dihydrate)
EINECS	Contact for details

Quality Control

Our Quinine Hydrochloride Dihydrate is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	7.0% - 10.0%
Specific Rotation	-223° to -229° (c = 2 in 0.1M HCl)
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.