Description

Rutaecarpine is a bioactive quinazolinocarboline alkaloid derived from *Evodia rutaecarpa* and other medicinal plants. This compound is of significant interest for its role as a key reference standard and active pharmaceutical ingredient (API) intermediate in research and development. It is primarily utilized by the pharmaceutical, nutraceutical, and academic research sectors for applications in cardiovascular, metabolic, and neurological studies.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and a lead compound for synthesizing novel drug candidates targeting various biological pathways.
• Cardiovascular Studies: Investigated for its potential vasodilatory and anti-hypertensive properties in preclinical research.
• Metabolic Disorder Research: Used in studies exploring its effects on lipid metabolism, insulin sensitivity, and related metabolic functions.
• Neurological Research: Employed as a tool compound in neuroscience to study its interactions with neurotransmitter systems and neuroprotective potential.
• Natural Product Standardization: Acts as a marker compound for the quality control and standardization of herbal extracts containing *Evodia rutaecarpa*.
• Biochemical Assays: Utilized in high-throughput screening and in vitro assays to evaluate biological activity and mechanism of action.

Basic Information

Product Name	Rutaecarpine
CAS No.	84-26-4
Molecular Formula	C₁₈H₁₃N₃O
Molecular Weight	287.31 g/mol
Synonyms	Rutecarpine; 8,13-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one; Evodiamine isomer; NSC 169853; Goshuyuamide II
EINECS	201-517-6

Quality Control

Our Rutaecarpine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis to ensure it meets high-purity standards suitable for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and in original packaging until use to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.