Description

Nicotine CAS NO 54-11-5 is a potent alkaloid and the principal psychoactive component found in tobacco plants. It is a critical intermediate and active ingredient for a wide range of pharmaceutical, agrochemical, and research applications. This compound is essential for manufacturers in the pharmaceutical industry developing nicotine replacement therapies (NRTs), as well as for researchers in toxicology and neuropharmacology.

Application

• Pharmaceutical Intermediates: Primary active ingredient in nicotine patches, gums, lozenges, and inhalers for smoking cessation therapies.
• Agrochemical Formulations: Key component in the synthesis of neonicotinoid insecticides and other botanical pesticides.
• Biochemical Research: Standard and reagent for studying nicotinic acetylcholine receptors (nAChRs) in neurological and behavioral research.
• Analytical Reference Standards: Certified reference material (CRM) for quality control and forensic analysis in tobacco and pharmaceutical products.
• E-liquid Production: Used in the manufacture of nicotine solutions for electronic cigarettes (subject to regional regulations and purity standards).

Basic Information

Item	Detail
Product Name	Nicotine
CAS No.	54-11-5
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	(-)-Nicotine; (S)-3-(1-Methyl-2-pyrrolidinyl)pyridine; L-Nicotine; (S)-Nicotine; 1-Methyl-2-(3-pyridyl)pyrrolidine; Nicotin; β-Pyridyl-α-N-methylpyrrolidine; Black Leaf 40
EINECS	200-193-3

Quality Control

Our Nicotine is produced and tested under stringent quality management systems. We offer grades suitable for pharmaceutical and research applications, with comprehensive testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each batch, detailing key parameters such as assay, optical rotation, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) at controlled room temperature (15-25°C) to minimize oxidation and volatility. Keep away from heat, open flames, and incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow, oily liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0% (anhydrous basis)
Specific Optical Rotation	-154° to -168° (c=2, in ethanol)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.