Description

Catharanthine CAS NO 2468-21-5 is a monoterpenoid indole alkaloid of significant pharmaceutical interest, primarily isolated from the Madagascar periwinkle plant (*Catharanthus roseus*). This compound serves as a crucial biosynthetic precursor in the production of complex dimeric alkaloids, most notably the potent anticancer agents vinblastine and vincristine. It is an essential intermediate for research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in oncology drug development, phytochemical research, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key starting material in the semi-synthesis of vital anticancer drugs vinblastine and vincristine.
• Biochemical Research: Used in studies of alkaloid biosynthesis pathways and enzyme mechanisms within plants.
• Reference Standard: Serves as a high-purity analytical standard for quality control in herbal extract and pharmaceutical manufacturing.
• Medicinal Chemistry: Employed as a building block for the research and development of novel indole alkaloid derivatives with potential therapeutic activity.
• Natural Product Isolation: A target compound for extraction and purification processes in the nutraceutical and phytochemical industries.

Basic Information

Product Name	Catharanthine
CAS No.	2468-21-5
Molecular Formula	C21H24N2O2
Molecular Weight	336.43 g/mol
Synonyms	Catharanthine; (19S)-19,20-Dihydro-19-(hydroxymethyl)ibogamine-18-carboxylic acid methyl ester; 3,4-Didehydroibogaine-18-carboxylic acid methyl ester; NSC 169642; (-)-Catharanthine; Vincamedine
EINECS	219-571-4

Quality Control

Our Catharanthine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets the stringent requirements for pharmaceutical intermediate and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.