Description

Mesembrine is a principal psychoactive alkaloid derived from the plant *Sceletium tortuosum* (Kanna). This compound is of significant commercial and research interest due to its unique pharmacological profile as a serotonin reuptake inhibitor. It is primarily sought by manufacturers in the nutraceutical, pharmaceutical research, and botanical extract industries for product development and analytical reference standards.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in studies targeting mood and cognitive support.
• Nutraceutical Formulations: Incorporated into dietary supplements and herbal blends designed to promote emotional well-being and relaxation.
• Analytical Chemistry: Serves as a high-purity certified reference material (CRM) for HPLC, LC-MS, and other analytical method development and quality control.
• Botanical Extract Standardization: Used to standardize and quantify the alkaloid content in *Sceletium tortuosum* (Kanna) extracts for consistent product potency.
• Cosmeceutical Applications: Explored in premium skincare formulations for its potential soothing properties.

Basic Information

Product Name	Mesembrine
CAS No.	468-53-1
Molecular Formula	C17H23NO3
Molecular Weight	289.37 g/mol
Synonyms	Mesembrine; (3aR,7aS)-2,3,4,5,7,7a-Hexahydro-1H-indol-6-one, 3a-(3,4-dimethoxyphenyl)octahydro-; 3a-(3,4-Dimethoxyphenyl)octahydro-2,3,4,5,7,7a-hexahydro-1H-indol-6-one; Kanna Alkaloid; Sceletium Alkaloid A
EINECS	Contact for details

Quality Control

Our Mesembrine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis to ensure it meets stringent specifications for research and commercial use. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.