Description

L-Hyoscyamine is a naturally occurring tropane alkaloid and the levorotatory isomer of hyoscyamine, known for its potent anticholinergic and antispasmodic properties. This high-purity active pharmaceutical ingredient (API) is critical for the development and manufacturing of effective therapeutic formulations. It is primarily required by pharmaceutical companies, research institutions, and fine chemical suppliers serving the global healthcare sector.

Application

• Pharmaceutical API: Core active ingredient in prescription medications for gastrointestinal disorders, including irritable bowel syndrome (IBS) and peptic ulcers.
• Antispasmodic Formulations: Used in drugs designed to relieve smooth muscle spasms in the digestive, urinary, and respiratory tracts.
• Pre-Anesthetic Medication: Employed to reduce salivary and bronchial secretions before surgery.
• Ophthalmic Solutions: Utilized in eye drops for procedures like refraction examinations and treating uveitis.
• Analytical Reference Standard: Serves as a certified standard for quality control and research in analytical laboratories.
• Biochemical Research: Used in pharmacological studies to investigate muscarinic acetylcholine receptor function and signal transduction pathways.

Basic Information

Item	Detail
Product Name	L-Hyoscyamine
CAS No.	101-31-5
Molecular Formula	C17H23NO3
Molecular Weight	289.37 g/mol
Synonyms	(-)-Hyoscyamine; Levohyoscyamine; Daturine; Atroscine; (3S)-Tropanyl (2S)-3-hydroxy-2-phenylpropanoate; 1αH,5αH-Tropan-3α-ol (-)-tropate; Belladonnine
EINECS	202-933-0

Quality Control

Our L-Hyoscyamine is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards, with specifications aligning with major pharmacopoeial requirements. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Specific Rotation	-20° to -23° (c = 2 in H2O)
Related Substances (HPLC)	Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.