Description

Muscimol is a potent psychoactive isoxazole alkaloid, primarily known as the principal psychoactive constituent of the mushroom *Amanita muscaria*. This compound is of significant interest in the global market for its specific neuropharmacological activity. It serves as a highly selective agonist for the GABAA receptor, making it a critical reference standard and research tool for neuroscientists and pharmaceutical developers. Key industries requiring this high-purity compound include pharmaceutical R&D, academic research institutions, and forensic laboratories focused on neurochemistry and toxicology.

Application

• Neuroscience Research: Used as a selective GABAA receptor agonist to study receptor function, neurotransmission, and the effects on the central nervous system.
• Pharmaceutical Reference Standard: Serves as a primary chemical reference material (CRM) for the quality control and assay development of related pharmaceutical compounds.
• Toxicology & Forensic Analysis: Employed as an analytical standard for the detection and quantification of muscimol in biological samples and forensic investigations.
• Biochemical Pathway Studies: A key tool for investigating the GABAergic system's role in various physiological and pathological conditions.
• Pharmacology Development: Used in early-stage drug discovery for screening and evaluating new compounds targeting GABA receptors.

Basic Information

Product Name	Muscimol
CAS No.	2763-96-4
Molecular Formula	C4H6N2O2
Molecular Weight	114.10 g/mol
Synonyms	5-(Aminomethyl)-3-isoxazolol; Agarin; Pantherine; 3-Hydroxy-5-aminomethylisoxazole; GABAA receptor agonist; Muscimole; (5-Aminomethyl-3-hydroxyisoxazole)
EINECS	220-420-2

Quality Control

Every batch of our Muscimol is produced and tested under strict quality management protocols to ensure the highest standards of purity and identity. We provide comprehensive analytical documentation, including a detailed Certificate of Analysis (COA) for each lot, which confirms compliance with in-house specifications. Our quality systems are designed to meet the rigorous demands of research and development applications, ensuring reliable and reproducible results for our clients worldwide.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.