Description

2-Bromo-6Beta-Fluoro-17,21-Dihydroxypregna-1,4,9(11)-Triene-3,20-Dione 17,21-Di(Acetate) is a high-purity, synthetic steroid derivative with a complex halogenated structure, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in enabling the synthesis of novel therapeutic agents, particularly in the fields of endocrinology and anti-inflammatory drug discovery. This compound is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions focused on developing next-generation steroid-based pharmaceuticals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel corticosteroid analogs and other potent steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry programs to explore structure-activity relationships (SAR) and develop new drug candidates targeting hormonal pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of specialized steroid compounds.
• Biochemical Research: Utilized in studies investigating steroid receptor binding and metabolic pathways.

Basic Information

Product Name	2-Bromo-6Beta-Fluoro-17,21-Dihydroxypregna-1,4,9(11)-Triene-3,20-Dione 17,21-Di(Acetate)
CAS No.	57808-78-3
Molecular Formula	C₂₅H₂₈BrFO₆
Molecular Weight	523.39 g/mol
Synonyms	9(11)-Dehydro-6β-fluoro-2-bromoprednisolone 17,21-diacetate; 2-Bromo-6β-fluoro-17α,21-dihydroxypregna-1,4,9(11)-triene-3,20-dione 17,21-diacetate; 2-Bromo-6β-fluoroprednisolone 17,21-diacetate; 6β-Fluoro-2-bromoprednisolone diacetate; 2-Bromo-6-fluoro-17,21-dihydroxypregna-1,4,9(11)-triene-3,20-dione diacetate; 57808-78-3; 2-Bromo-6β-fluoro-17α,21-dihydroxy-1,4,9(11)-pregnatriene-3,20-dione 17,21-diacetate
EINECS	Contact for details

Quality Control

Our 2-Bromo-6Beta-Fluoro-17,21-Dihydroxypregna-1,4,9(11)-Triene-3,20-Dione 17,21-Di(Acetate) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.