Description

2-Bromo-9Beta,11Beta-Epoxy-6Beta-Fluoro-17,21-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 17,21-Di(Acetate) is a sophisticated, multi-functional steroid derivative with a complex halogenated and epoxidized structure. This compound matters as a critical advanced pharmaceutical intermediate for the research and development of novel steroidal drugs, particularly in the fields of anti-inflammatory and anti-cancer therapeutics. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of high-potency active pharmaceutical ingredients (APIs).

Application

• Key Intermediate in Steroid Drug Synthesis: Serves as a crucial building block for the production of novel glucocorticoid receptor modulators.
• Pharmaceutical Research & Development: Used in medicinal chemistry programs to develop new anti-inflammatory and immunosuppressive agents with potentially improved efficacy and safety profiles.
• Preclinical Studies: Employed in the synthesis of reference standards and experimental compounds for pharmacological evaluation and metabolic pathway studies.
• Process Chemistry Development: Utilized by process chemists to develop and scale up efficient synthetic routes for complex steroid-based APIs.
• Academic Research: Applied in university and institutional laboratories for studying structure-activity relationships (SAR) of halogenated steroids.

Basic Information

Product Name	2-Bromo-9Beta,11Beta-Epoxy-6Beta-Fluoro-17,21-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 17,21-Di(Acetate)
CAS No.	57789-28-3
Molecular Formula	C₂₈H₃₂BrFO₇
Molecular Weight	579.46 g/mol
Synonyms	9β,11β-Epoxy-6β-fluoro-2-bromo-16α-methylpregna-1,4-diene-3,20-dione 17,21-diacetate; 2-Bromo-6β-fluoro-9β,11β-epoxy-16α-methyl-17α,21-dihydroxypregna-1,4-diene-3,20-dione 17,21-diacetate; 2-Bromo-6β-fluoro-9β,11β-epoxy-16α-methylprednisolone 17,21-diacetate; Halogenated Prednisolone Derivative; Bromofluoro Epoxy Methylprednisolone Diacetate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Bromo-9Beta,11Beta-Epoxy-6Beta-Fluoro-17,21-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 17,21-Di(Acetate) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.