Description

2-Bromo-9,11Beta-Dichloro-6Beta-Fluoro-17,21-Dihydroxy-16Beta-Methylpregna-1,4-Diene-3,20-Dione 17,21-Di(Acetate) is a complex, multi-functional steroid derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a critical synthetic intermediate or reference standard for the development of novel corticosteroid analogs with potent anti-inflammatory and immunosuppressive activities. Pharmaceutical R&D teams and fine chemical manufacturers need this high-purity building block to explore new therapeutic pathways and ensure the quality and consistency of their development pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel, high-potency corticosteroid drugs.
• Active Pharmaceutical Ingredient (API) Development: Used in research to develop and characterize new steroid-based APIs targeting inflammation and autoimmune disorders.
• Reference Standard: Acts as an analytical standard in quality control laboratories for the identification and quantification of related steroid compounds.
• Biochemical Research: Employed in academic and industrial research to study steroid receptor interactions, metabolism, and structure-activity relationships (SAR).
• Process Chemistry: Utilized for scaling up synthetic routes and optimizing manufacturing processes for steroid-based pharmaceuticals.

Basic Information

Product Name	2-Bromo-9,11Beta-Dichloro-6Beta-Fluoro-17,21-Dihydroxy-16Beta-Methylpregna-1,4-Diene-3,20-Dione 17,21-Di(Acetate)
CAS No.	57781-61-0
Molecular Formula	C₂₆H₂₉BrCl₂FO₇
Molecular Weight	632.32 g/mol
Synonyms	9,11β-Dichloro-6β-fluoro-2-bromo-16β-methylpregna-1,4-diene-3,20-dione 17,21-diacetate; 2-Bromo-9α,11β-dichloro-6β-fluoro-16β-methylprednisolone 17,21-diacetate; 2-Bromo-9,11-dichloro-6-fluoro-16-methylprednisolone diacetate; 2-Bromodichlorofluoromethylprednisolone diacetate; 57781-61-0; Prednisolone derivative, 2-bromo-9,11-dichloro-6-fluoro-16-methyl-, 17,21-diacetate
EINECS	Contact for details

Quality Control

Our 2-Bromo-9,11Beta-Dichloro-6Beta-Fluoro-17,21-Dihydroxy-16Beta-Methylpregna-1,4-Diene-3,20-Dione 17,21-Di(Acetate) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity suitable for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.