Description

Halopredone is a synthetic corticosteroid derivative, a potent anti-inflammatory and immunosuppressive agent. Its primary value lies in its targeted pharmacological activity, making it a critical intermediate for advanced pharmaceutical research and development. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly those developing novel topical and systemic corticosteroid therapies.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of potent corticosteroid APIs (Active Pharmaceutical Ingredients).
• Anti-inflammatory Drug Research: Used in preclinical and clinical research for developing new treatments for inflammatory conditions like dermatitis, psoriasis, and arthritis.
• Immunosuppressant Development: Investigated for applications in autoimmune disease therapies and organ transplant rejection prevention.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.
• Veterinary Medicine: Potential use in formulating anti-inflammatory treatments for animals.
• Biochemical Research: Tool compound for studying glucocorticoid receptor interactions and downstream signaling pathways.

Basic Information

Product Name	Halopredone
CAS No.	57781-15-4
Molecular Formula	C₂₂H₂₇ClF₂O₆
Molecular Weight	460.90 g/mol
Synonyms	Halopredone Acetate; 21-Acetoxy-6α,9-difluoro-11β-hydroxy-17α-methylpregna-1,4-diene-3,20-dione; 6α,9-Difluoro-11β,17α,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-acetate; SQ-15102; NSC-113179
EINECS	Contact for details

Quality Control

Our Halopredone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) documenting all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.