Description

9-Chloro-11Beta,17-Dihydroxy-16Beta-Methylpregna-1,4-Diene-3,20-Dione CAS NO 57780-87-7 is a high-purity synthetic steroid derivative, serving as a critical pharmaceutical intermediate. Its value lies in its role as a key building block for the synthesis of advanced corticosteroid and anti-inflammatory APIs, ensuring precise molecular structure for downstream efficacy. This compound is essential for R&D and production within the pharmaceutical, biotechnology, and fine chemical sectors, where stringent quality and structural integrity are paramount.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of potent corticosteroid drugs, including anti-inflammatory and immunosuppressive agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for the research and development of novel steroid-based therapeutics.
• Biochemical Research: Used as a reference standard or probe in steroid receptor binding studies and metabolic pathway research.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for complex steroid molecules in fine chemical manufacturing.
• Veterinary Pharmaceutical Synthesis: A precursor in the production of anti-inflammatory treatments for animal health applications.

Basic Information

Product Name	9-Chloro-11Beta,17-Dihydroxy-16Beta-Methylpregna-1,4-Diene-3,20-Dione
CAS No.	57780-87-7
Molecular Formula	C22H29ClO4
Molecular Weight	392.92 g/mol
Synonyms	9-Chloro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione; 9-Chloro-16β-methylprednisolone; 9-Chloro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione; 9-Chloro-16β-methyl-δ1,4-pregnadiene-11β,17α,21-triol-3,20-dione; 9-Chloro-16-methylprednisolone; Clobetasol Propionate Intermediate; Betamethasone-17,21-dipropionate related compound
EINECS	Contact for details

Quality Control

Our 9-Chloro-11Beta,17-Dihydroxy-16Beta-Methylpregna-1,4-Diene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure compliance with pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided to guarantee supply chain transparency and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.