Description

Sequifenadine is a high-purity pharmaceutical intermediate and active ingredient with significant commercial and research value. It is essential for the development and production of advanced therapeutic agents, particularly in the antihistamine and anti-inflammatory domains. This compound is primarily sought by manufacturers and R&D laboratories in the global pharmaceutical, biotechnology, and fine chemical sectors for its critical role in synthesis and formulation processes.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of antihistamine medications.
• Advanced Drug Synthesis: Key intermediate in multi-step organic synthesis for novel therapeutic compounds.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological and metabolic studies.
• Fine Chemical Production: Serves as a building block for creating more complex, specialized molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for GMP production.
• Analytical Standard: Provides a certified reference material for quality control and regulatory testing in labs.

Basic Information

Product Name	Sequifenadine
CAS No.	57734-69-7
Molecular Formula	C21H24N2O2
Molecular Weight	336.43 g/mol
Synonyms	Sequifenadine; 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-butanone; Bicarphen; Sequifenadine Hydrochloride (salt form); Bikarfen; Sequifenadin; 4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-[4-(tert-butyl)phenyl]-1-butanone
EINECS	Contact for details

Quality Control

Our Sequifenadine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.