Description

Dehydro Berberrubine Bromide is a high-purity, semi-synthetic alkaloid derivative of significant interest in advanced research and development. This compound serves as a critical reference standard and key intermediate for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in developing new therapeutic agents and studying natural product chemistry.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of berberine-related compounds in drug development and quality control.
• Biochemical Research: Acts as a key intermediate or probe in studies investigating enzyme inhibition, receptor binding, and other cellular mechanisms.
• Organic Synthesis: Serves as a versatile building block for the semi-synthesis of novel alkaloid derivatives with potential pharmacological activity.
• Analytical Chemistry: Employed as a calibration standard in chromatographic methods (HPLC, LC-MS) for method development and validation.
• Natural Product Chemistry: Used in comparative studies and as a precursor for generating analogs to explore structure-activity relationships (SAR).

Basic Information

Product Name	Dehydro Berberrubine Bromide
CAS No.	57721-67-2
Molecular Formula	C19H14BrNO4
Molecular Weight	400.22 g/mol
Synonyms	Dehydroberberrubine Bromide; 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-7-ium, Bromide; Berberrubine Bromide, Dehydro-; 7,8-Didehydro-2,3-dimethoxy-13-methyl-5,6,13,13a-tetrahydro-9H-[1,3]dioxolo[4,5-g]isoquinolino[2,1-b]isoquinolin-9-one Bromide
EINECS	Contact for details

Quality Control

Our Dehydro Berberrubine Bromide is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and mass spectrometry. We adhere to cGMP principles where applicable to support our clients in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.