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n-[3-[4-[2-Hydroxy-3-[(1-Methylethyl)Amino]Propoxy]Phenyl]Propyl]Acetamide CAS NO 57494-84-5
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CAS No.:57494-84-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-[3-[4-[2-Hydroxy-3-[(1-Methylethyl)Amino]Propoxy]Phenyl]Propyl]Acetamide is a high-purity, synthetically derived organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical intermediate or active pharmaceutical ingredient (API) in the synthesis of targeted therapeutic agents. It is primarily required by pharmaceutical manufacturers and R&D organizations focused on developing new drug candidates, particularly in the cardiovascular and metabolic disease sectors.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of proprietary β-blocker or related cardiovascular APIs.
- Active Pharmaceutical Ingredient (API): Potential use as the core active component in formulated drug products targeting specific receptor pathways.
- Biochemical Research: Used as a reference standard or probe compound in pharmacological studies and receptor binding assays.
- Process Development: Serves as a critical material for scaling up and optimizing synthetic routes in pilot plants and commercial manufacturing.
- Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials or commercial batches.
- Analytical Standard: Employed in quality control laboratories for method development, validation, and impurity profiling via HPLC, GC, or LC-MS.
Basic Information
| Product Name | n-[3-[4-[2-Hydroxy-3-[(1-Methylethyl)Amino]Propoxy]Phenyl]Propyl]Acetamide |
| CAS No. | 57494-84-5 |
| Molecular Formula | C17H28N2O3 |
| Molecular Weight | 308.42 g/mol |
| Synonyms | N-[3-[4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl]propyl]acetamide; 1-[4-[3-(Acetylamino)propyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol; Acebutolol Impurity; Acebutolol Related Compound; 2-Propanol, 1-[4-[3-(acetylamino)propyl]phenoxy]-3-[(1-methylethyl)amino]-; UNII-6Q4A8W5W5F |
| EINECS | Contact for details |
Quality Control
Our n-[3-[4-[2-Hydroxy-3-[(1-Methylethyl)Amino]Propoxy]Phenyl]Propyl]Acetamide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent control of residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Related Substances (HPLC) | Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5% |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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