Description

Talinolol is a selective β-1 adrenergic receptor antagonist (β-blocker) with cardioselective properties. This compound is of significant interest in pharmaceutical research and development for its potential therapeutic applications. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of cardiovascular medications and pharmacological studies. Talinolol CAS NO 57460-41-0 serves as a key intermediate or reference standard in these critical processes.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel β-blocker drug candidates.
• Reference Standard: For analytical method development, validation, and quality control in pharmaceutical laboratories.
• Pharmacological Studies: Used in preclinical research to investigate β-1 adrenergic receptor activity, cardioselectivity, and metabolic pathways.
• Academic Research: Employed in university and institutional labs for chemical and biological studies related to cardiovascular agents.
• Impurity Standard: Serves as a certified reference material for identifying and quantifying related substances in active pharmaceutical ingredient (API) batches.

Basic Information

Product Name	Talinolol
CAS No.	57460-41-0
Molecular Formula	C20H33N3O4
Molecular Weight	379.49 g/mol
Synonyms	Cordanum; Talinololum; (±)-1-[4-[3-(tert-Butylamino)-2-hydroxypropoxy]phenyl]-3-cyclohexylurea; 1-[4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-3-cyclohexylurea; UNII-4V5Y1C31QN; BRN 3911957; 4-[3-(tert-Butylamino)-2-hydroxypropoxy]phenylcyclohexylurea
EINECS	Contact for details

Quality Control

Our Talinolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via techniques such as HPLC, to ensure it meets high-grade standards suitable for research applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.