Description

4-Amino-3-Methyl-2-(Trifluoromethyl)Benzonitrile is a high-purity, multi-functional aromatic nitrile building block distinguished by its trifluoromethyl and amino substituents. This compound is valued for its role as a critical intermediate in advanced organic synthesis, enabling the introduction of both electron-withdrawing and electron-donating groups into complex molecular architectures. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of molecules containing trifluoromethyl motifs, which are prevalent in modern drug discovery for their metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the benzonitrile core and fluorine atoms contribute to biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its rigid aromatic structure and polar functional groups.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions, cyclizations, and as a starting material for heterocyclic compounds like quinazolines and benzimidazoles in academic and industrial R&D settings.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments, where the amino and cyano groups allow for further functionalization and color tuning.

Basic Information

Item	Details
Product Name	4-Amino-3-Methyl-2-(Trifluoromethyl)Benzonitrile
CAS No.	57376-86-0
Molecular Formula	C9H7F3N2
Molecular Weight	200.16 g/mol
Synonyms	2-Cyano-6-methyl-3-(trifluoromethyl)aniline; 2-Amino-6-methyl-α,α,α-trifluoro-m-toluonitrile; 3-Methyl-4-amino-2-trifluoromethylbenzonitrile; 4-Amino-3-methyl-α,α,α-trifluoro-o-toluonitrile; 2-Trifluoromethyl-4-amino-3-methylbenzonitrile; 6-Methyl-3-trifluoromethylanthranilonitrile; 2-Amino-6-methyl-3-trifluoromethylbenzonitrile; 4-Amino-3-methyl-2-trifluoromethylbenzonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-3-Methyl-2-(Trifluoromethyl)Benzonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and production. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.