Description

Bunitrolol Hydrochloride CAS NO 57371-64-9 is a pharmaceutical-grade β-adrenergic blocking agent (β-blocker) used in research and development. This compound is critical for cardiovascular research, serving as a key intermediate or reference standard in the synthesis and study of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) focusing on cardiology and hypertension.

Application

• Pharmaceutical Research & Development: As a reference standard or intermediate in the synthesis of β-blocker drugs.
• Cardiovascular Studies: For in-vitro and in-vivo pharmacological research targeting β-adrenergic receptors.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used as a starting material or intermediate in the production of finished dosage forms.
• Analytical Method Development: Serves as a high-purity standard for HPLC, LC-MS, and other chromatographic techniques.
• Metabolism and Pharmacokinetics Studies: Investigation of drug absorption, distribution, metabolism, and excretion (ADME).
• Quality Control Laboratories: Used for system suitability testing and as a comparator in identity and assay tests.

Basic Information

Product Name	Bunitrolol Hydrochloride
CAS No.	57371-64-9
Molecular Formula	C17H20N2O3·HCl
Molecular Weight	336.81 g/mol
Synonyms	Bunitrolol HCl; 2-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]benzonitrile monohydrochloride; (±)-Bunitrolol Hydrochloride; Koe 1366; Bunitrolol Hydrochloride (USAN); Benzonitrile, 2-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-, monohydrochloride; 1-(tert-Butylamino)-3-(o-cyanophenoxy)-2-propanol Hydrochloride
EINECS	Contact for details

Quality Control

Our Bunitrolol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.