Description

2-Nitro-1-(2-Oxopropyl)-4-Trifluoromethoxybenzene is a specialized organic intermediate featuring a nitro group and a trifluoromethoxy substituent on a benzene ring, which imparts unique electronic and steric properties. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethoxy group can contribute to improved lipophilicity and biological activity.
• Material Science: Acts as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed in academic and industrial laboratories for methodological studies in organic chemistry, particularly in reactions involving nitroarenes and ketones.
• Ligand and Catalyst Development: Utilized as a scaffold for designing novel ligands in catalytic systems or as a component in metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Nitro-1-(2-Oxopropyl)-4-Trifluoromethoxybenzene
CAS No.	57330-59-3
Molecular Formula	C10H8F3NO4
Molecular Weight	263.17 g/mol
Synonyms	1-(2-Nitro-4-(trifluoromethoxy)phenyl)propan-2-one; 2-Nitro-4-(trifluoromethoxy)propiophenone; 4-Trifluoromethoxy-2-nitropropiophenone; 1-(4-Trifluoromethoxy-2-nitrophenyl)acetone; 2-Nitro-1-(2-oxopropyl)-4-(trifluoromethoxy)benzene; α-Acetonyl-2-nitro-4-trifluoromethoxybenzene; 57330-59-3; 2-Nitro-4-trifluoromethoxypropiophenone
EINECS	Contact for details

Quality Control

Our 2-Nitro-1-(2-Oxopropyl)-4-Trifluoromethoxybenzene is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.