Description

Methyl 20-Dihydroprednisolonate CAS NO 57073-10-6 is a key synthetic steroid intermediate, specifically a methylated derivative of dihydroprednisolone. This compound is valued for its role as a crucial building block in the synthesis of advanced corticosteroid pharmaceuticals and other high-potency steroid-based active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract synthesis organizations engaged in the development and production of anti-inflammatory and immunosuppressive medications.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent topical and systemic corticosteroids.
• API Development: Used in research and development for creating novel steroid-based active pharmaceutical ingredients with modified pharmacokinetic profiles.
• Anti-inflammatory Drug Synthesis: Serves as a building block for manufacturing drugs targeting inflammation, autoimmune disorders, and allergic conditions.
• Biochemical Research: Employed in academic and industrial laboratories for studying steroid receptor interactions and metabolic pathways.
• Process Chemistry: Utilized in scale-up and optimization of steroid manufacturing processes for commercial production.

Basic Information

Product Name	Methyl 20-Dihydroprednisolonate
CAS No.	57073-10-6
Molecular Formula	C23H30O5
Molecular Weight	386.48 g/mol
Synonyms	20-Dihydro-20-methylprednisolonate; Methyl 20-dihydroprednisolonate; 11β,17α,21-Trihydroxy-20-methylpregna-1,4-diene-3,11,20-trione; 20-Methylprednisolone-20,21-acetonide related compound; 20-Methyl-20-dihydroprednisolone; Prednisolone, 20-methyl-20-dihydro-; 20-Methyl-11β,17α,21-trihydroxypregna-1,4-diene-3,11,20-trione
EINECS	Contact for details

Quality Control

Our Methyl 20-Dihydroprednisolonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and control of specific impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.