Description

4-(2,2,2-Trifluoroethoxy)Benzonitrile is a high-purity, versatile fluorinated aromatic nitrile building block essential for advanced chemical synthesis. Its molecular structure, featuring a trifluoroethoxy side chain, provides unique electronic and steric properties that are critical for developing novel active compounds. This intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents with enhanced efficacy and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoroethoxy group can improve lipophilicity and biological activity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs) due to its ability to modify dielectric anisotropy and viscosity.
• Organic Electronics: Employed in the development of novel organic semiconductors, electron-transport materials, and non-linear optical (NLO) materials for optoelectronic devices.
• Advanced Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, including polyimides and polyesters, to enhance thermal stability, chemical resistance, and optical properties.
• Chemical Research & Development: A valuable building block in academic and industrial R&D for exploring new reactions, catalytic processes, and material science applications.

Basic Information

Product Name	4-(2,2,2-Trifluoroethoxy)Benzonitrile
CAS No.	56935-76-3
Molecular Formula	C9H6F3NO
Molecular Weight	201.15 g/mol
Synonyms	p-(2,2,2-Trifluoroethoxy)benzonitrile; 4-(Trifluoroethoxy)benzonitrile; 1-Cyano-4-(2,2,2-trifluoroethoxy)benzene; Benzonitrile, 4-(2,2,2-trifluoroethoxy)-; 4-Trifluoroethoxybenzonitrile; α,α,α-Trifluoro-p-cyanophenetole; 4-Cyanophenyl 2,2,2-trifluoroethyl ether
EINECS	Contact for details

Quality Control

Every batch of 4-(2,2,2-Trifluoroethoxy)Benzonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure compliance with exacting purity standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.