Description

2,2,2-Trifluoro-n-[2-Hydroxy-2-(4-Hydroxy-3-Methoxyphenyl)Ethyl]Acetamide is a high-purity fluorinated acetamide derivative with a distinct phenolic and ethanolamine-like structure. This compound is valued for its role as a key synthetic intermediate in advanced pharmaceutical and agrochemical research, enabling the introduction of trifluoromethyl and specific aromatic functionalities. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and life science industries for constructing complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, particularly those targeting the central nervous system or requiring metabolic stability.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Fluorine Chemistry: Acts as a versatile reagent for introducing fluorine atoms into complex organic molecules, a common strategy in modern medicinal chemistry.
• Bioconjugation & Probe Synthesis: Utilized in creating fluorescent probes or affinity labels for biochemical and diagnostic applications due to its reactive hydroxyl and amide groups.
• Material Science Precursor: Investigated as a monomer or additive for specialty polymers where fluorine content imparts unique surface properties or chemical resistance.

Basic Information

Product Name	2,2,2-Trifluoro-n-[2-Hydroxy-2-(4-Hydroxy-3-Methoxyphenyl)Ethyl]Acetamide
CAS No.	56805-13-1
Molecular Formula	C11H12F3NO4
Molecular Weight	279.21 g/mol
Synonyms	N-[2-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)ethyl]-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-[2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)ethyl]acetamide; 1-(4-Hydroxy-3-methoxyphenyl)-2-[(2,2,2-trifluoroacetyl)amino]ethanol; Trifluoroacetamide vanillyl ethanolamine derivative
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-[2-Hydroxy-2-(4-Hydroxy-3-Methoxyphenyl)Ethyl]Acetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed after use to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.