Description

Higenamine-1-Carboxylic Acid is a key synthetic intermediate and derivative of higenamine, a naturally occurring alkaloid. This compound is valued for its role as a versatile building block in organic synthesis and pharmaceutical research. It is primarily utilized by manufacturers and R&D laboratories in the pharmaceutical, nutraceutical, and fine chemical sectors for developing active pharmaceutical ingredients (APIs) and other high-value compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of higenamine-based APIs and other alkaloid derivatives for cardiovascular and metabolic research.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control testing in laboratories.
• Biochemical Research: Employed in studies investigating β-adrenergic receptor activity and related biochemical pathways.
• Nutraceutical Development: Serves as a starting material for the development of standardized botanical extracts and dietary supplement ingredients.
• Organic Synthesis: Acts as a versatile chiral building block for constructing complex molecules in medicinal chemistry.

Basic Information

Product Name	Higenamine-1-Carboxylic Acid
CAS No.	56632-94-1
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	1-Carboxyhigenamine; Norcoclaurine-1-carboxylic acid; (1R,2S)-1-(4-Hydroxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid; Higenamine carboxylic acid; Demethylcoclaurine-1-carboxylic acid; Higenamine-1-COOH
EINECS	Contact for details

Quality Control

Our Higenamine-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.