Description

Metoprolol Tartrate is a selective β-1 adrenergic receptor blocking agent, widely recognized for its cardiovascular applications. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of finished dosage forms. It is primarily utilized by pharmaceutical manufacturers in the production of medications for hypertension, angina, and heart failure management.

Application

• Pharmaceutical API: Primary use as the active ingredient in solid oral dosage forms (tablets, capsules) for cardiovascular therapy.
• Hypertension Treatment: Formulated into medications designed to lower high blood pressure by reducing cardiac output.
• Angina Pectoris Management: Used in drugs that prevent chest pain by decreasing the heart's workload and oxygen demand.
• Heart Failure Therapy: Incorporated into treatment regimens to improve survival and reduce hospitalizations in certain patients.
• Post-Myocardial Infarction: A key component in secondary prevention protocols following a heart attack.
• Reference Standard: Serves as a high-purity analytical standard in quality control laboratories for method development and validation.
• Research & Development: Used in preclinical and clinical studies for developing new cardiovascular drug formulations and delivery systems.

Basic Information

Product Name	Metoprolol Tartrate
CAS No.	56392-17-7
Molecular Formula	C34H56N2O12
Molecular Weight	684.82 g/mol
Synonyms	Metoprolol Acid Tartrate; (±)-Metoprolol Tartrate; 1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol L-(+)-Tartrate (2:1); Lopressor; Betaloc; Seloken; Toprol-XL; CGP 2175
EINECS	260-154-1

Quality Control

Our Metoprolol Tartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity pharmacopeial standards (such as USP/EP) for identity, assay, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Optical Rotation	-0.10° to +0.10°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.