Description

Pregnane-3,20-Dione, 21-(Acetyloxy)-11,17-Dihydroxy- is a high-purity steroid derivative, a key intermediate in the synthesis of potent glucocorticoids. This compound matters for its critical role in pharmaceutical research and development, enabling the production of advanced anti-inflammatory and immunosuppressive agents. It is primarily needed by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers focused on steroid chemistry and advanced drug synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of potent corticosteroid APIs (Active Pharmaceutical Ingredients).
• Glucocorticoid Research: Used in the research and development of novel anti-inflammatory and immunosuppressive drugs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in process development and scale-up for the commercial manufacturing of steroid-based therapeutics.
• Biochemical Studies: Utilized in metabolic and receptor-binding studies to understand glucocorticoid action and metabolism.

Basic Information

Product Name	Pregnane-3,20-Dione, 21-(Acetyloxy)-11,17-Dihydroxy-
CAS No.	56193-59-0
Molecular Formula	C₂₃H₃₂O₆
Molecular Weight	404.50 g/mol
Synonyms	21-Acetoxypregnenolone; 21-Acetoxy-11β,17α-dihydroxypregn-4-ene-3,20-dione; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 21-acetate; Cortisol 21-acetate; Hydrocortisone 21-acetate; Reichstein's Substance S 21-acetate; 11β,17α-Dihydroxy-21-(acetyloxy)pregn-4-ene-3,20-dione
EINECS	Contact for details

Quality Control

Our Pregnane-3,20-Dione, 21-(Acetyloxy)-11,17-Dihydroxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.