Description

Nitro(Trifluoromethyl)Benzene CAS NO 56142-29-1 is a high-purity fluorinated aromatic building block, essential for introducing both nitro and trifluoromethyl functional groups into complex molecular architectures. This compound is valued for its role in modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of compounds targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic displays and organic light-emitting diodes (OLEDs), improving charge transport and device performance.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, and surface properties for high-performance coatings and engineering plastics.
• Dye & Pigment Intermediate: Employed in the synthesis of novel, light-fast fluorinated dyes and pigments for specialized applications.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) for constructing complex biaryl systems in medicinal chemistry.

Basic Information

Product Name	Nitro(Trifluoromethyl)Benzene
CAS No.	56142-29-1
Molecular Formula	C7H4F3NO2
Molecular Weight	191.11 g/mol
Synonyms	1-Nitro-3-(trifluoromethyl)benzene; 3-(Trifluoromethyl)nitrobenzene; m-Nitrobenzotrifluoride; m-Nitro-α,α,α-trifluorotoluene; 3-Nitrobenzotrifluoride; 3-Trifluoromethylnitrobenzene; Benzene, 1-nitro-3-(trifluoromethyl)-; α,α,α-Trifluoro-m-nitrotoluene
EINECS	260-025-5

Quality Control

Our Nitro(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the stringent requirements of our global B2B clients. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurity profiles is provided with every shipment. We support compliance with major regulatory frameworks including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%
Refractive Index (n20D)	1.460 - 1.470
Density (g/mL at 20°C)	1.40 - 1.45

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.