Description

Pglu-His-Trp-Ser-Tyr-D-Ala-n-Methyl-Leu-Arg-Pro-Gly-Nh2 is a synthetic peptide analog of gonadotropin-releasing hormone (GnRH). This compound is significant for its potent biological activity and high specificity in modulating hormonal pathways. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing diagnostic tools, therapeutic agents, and advanced biochemical research reagents.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) in the development of hormone-related therapies.
• Endocrinology Studies: Used in biochemical and physiological research to study the GnRH receptor mechanism and signal transduction.
• Diagnostic Manufacturing: Serves as a critical component in the production of immunoassay kits and diagnostic reagents for hormonal disorders.
• Peptide Synthesis & Conjugation: Acts as a building block or target molecule for the synthesis of more complex peptide conjugates and analogs.
• Academic & Institutional Research: Provides a high-purity tool for universities and research institutes conducting fundamental life science research.
• Veterinary Medicine: Potential applications in the development of reproductive health treatments for animals.

Basic Information

Product Name	Pglu-His-Trp-Ser-Tyr-D-Ala-n-Methyl-Leu-Arg-Pro-Gly-Nh2
CAS No.	56133-95-0
Molecular Formula	C₆₆H₉₁N₂₁O₁₆
Molecular Weight	1434.6 g/mol
Synonyms	GnRH Agonist Peptide; PGLU-HIS-TRP-SER-TYR-D-ALA-LEU(ME)-ARG-PRO-GLY-NH2; Des-Gly10, D-Ala6, N-Me-Leu7-Pro9-NHEt-GnRH; Luteinizing Hormone-Releasing Hormone (6-D-Alanine, 7-N-Methylleucine, 9-Proline, 10-Glycinamide); [Des-Gly10, D-Ala6, N-Me-Leu7, Pro9-NHEt]-LHRH; Gonadorelin (6-D-Ala, 7-N-Me-Leu, 9-Pro-NHEt) analog; PGLU-HIS-TRP-SER-TYR-D-ALA-N-METHYL-LEU-ARG-PRO-GLY-NH2
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of Pglu-His-Trp-Ser-Tyr-D-Ala-n-Methyl-Leu-Arg-Pro-Gly-Nh2 undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and cGMP-grade standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Composition	± 10% of theoretical
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.