Description

Dexamethasone Acetate, Monohydrate is a potent synthetic glucocorticoid ester, widely recognized for its anti-inflammatory and immunosuppressive properties. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of advanced pharmaceutical formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of injectable and topical corticosteroid medications.

Application

• Pharmaceutical API: Core ingredient in injectable and topical formulations for treating severe inflammation, allergic reactions, and autoimmune disorders.
• Ophthalmic Solutions: Used in eye drops and ointments to manage post-operative inflammation and uveitis.
• Dermatological Preparations: Key component in creams and ointments for treating eczema, psoriasis, and other inflammatory skin conditions.
• Veterinary Medicine: Employed in anti-inflammatory and anti-shock treatments for animals.
• Research & Development: Serves as a reference standard and a crucial compound in pharmacological and biochemical research.
• Hospital Compounding: Used in pharmacy compounding for customized patient-specific therapies.

Basic Information

Product Name	Dexamethasone Acetate, Monohydrate
CAS No.	55812-90-3
Molecular Formula	C24H31FO6 • H2O
Molecular Weight	434.50 g/mol (Monohydrate)
Synonyms	Dexamethasone 21-Acetate Monohydrate; 9α-Fluoro-16α-methylprednisolone 21-Acetate Monohydrate; Decadron Acetate; Dexasone Acetate; (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-acetate monohydrate
EINECS	Contact for details

Quality Control

Our Dexamethasone Acetate, Monohydrate is manufactured under strict quality management systems. Each batch is tested to ensure it meets stringent specifications for identity, purity, and potency, aligning with major pharmacopoeial standards such as USP and EP. A comprehensive Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	3.5% - 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	+77° to +82° (c=1 in dioxane)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.