Description

Preneocarzinostatin CAS NO 55608-09-8 is a potent enediyne antibiotic and antitumor agent derived from *Streptomyces* species. This compound is of significant interest in pharmaceutical research and development due to its unique mechanism of action, which involves DNA cleavage and potent cytotoxicity. It is primarily utilized by researchers and developers in the fields of oncology, biochemistry, and molecular biology for investigating novel cancer therapeutics and studying DNA-protein interactions.

Application

• Anticancer Research: Serves as a key reference standard and active pharmaceutical ingredient (API) in the study of novel chemotherapeutic agents and targeted cancer therapies.
• Biochemical Studies: Used as a molecular probe to investigate mechanisms of DNA damage, repair pathways, and the function of enediyne antibiotics.
• Pharmaceutical Development: Employed in the preclinical development and screening of new antitumor compounds and drug conjugates.
• Academic Research: Utilized in university and institutional laboratories for fundamental research in chemical biology and medicinal chemistry.
• Standards and Calibration: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	Preneocarzinostatin
CAS No.	55608-09-8
Molecular Formula	C35H48Cl2N6O12S2
Molecular Weight	879.82 g/mol
Synonyms	Pre-Neocarzinostatin; Pre-NCS; Neocarzinostatin Chromophore Precursor; NCS Chromophore Precursor; Antibiotic LC-51 Precursor; (1S,2R,3S,4S,5R,6S,7R,8R,9S,10R,11S,12R,13S,14R,15S,16R,17S,18R,19S,20R,21S,22R,23S,24R,25S,26R,27S,28R,29S,30R,31S,32R,33S,34R,35S)-35-[(2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-34-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31-hexadecahydroxy-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32-hexadecaoxa-33-azapentacyclo[30.2.1.1³,⁶.1⁸,¹¹.1¹³,¹⁶]pentatriacontane-33-carboxylic acid
EINECS	Contact for details

Quality Control

Our Preneocarzinostatin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade research specifications. Certificates of Analysis (COA) detailing purity, related substances, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.