Description

Aminoglutethimide is a synthetic, non-steroidal compound that acts as a selective aromatase inhibitor. This property makes it a critical intermediate in the research and development of therapeutic agents targeting hormone-dependent conditions. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers. The compound's specific mechanism of action underpins its importance in advanced medical and biochemical applications.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly those targeting endocrine pathways.
• Biochemical Research: Used as a reference standard or tool compound in laboratory studies investigating steroidogenesis, aromatase enzyme activity, and hormone metabolism.
• Oncology Research: Employed in preclinical research for developing and testing novel therapies for hormone-sensitive cancers, such as certain breast and prostate cancers.
• Reference Standard: Serves as a high-purity certified reference material (CRM) for quality control and analytical method development in pharmaceutical analysis.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry, pharmacology, and endocrinology.

Basic Information

Product Name	Aminoglutethimide
CAS No.	55511-45-0
Molecular Formula	C13H16N2O2
Molecular Weight	232.28 g/mol
Synonyms	3-(4-Aminophenyl)-3-ethylpiperidine-2,6-dione; (±)-Aminoglutethimide; DL-Aminoglutethimide; 3-Ethyl-3-(4-aminophenyl)piperidine-2,6-dione; Cytadren (brand name); Orimeten; Elipten; AG; Amino-Glutethimide
EINECS	Contact for details

Quality Control

Our Aminoglutethimide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets exacting standards for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.