Description

(20R)-3α-[(5,5-Dimethyl-3-Oxo-1-Cyclohexen-1-Yl)Amino]-20-Hydroxypregn-5-En-18-Oic Acid γ-Lactone is a high-purity, specialized steroid derivative with a complex molecular architecture. This compound is valued for its role as a critical advanced pharmaceutical intermediate in the synthesis of novel therapeutic agents, particularly within the field of endocrinology and hormone research. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of steroidal drugs and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel steroidal drugs and hormone analogs.
• Biochemical Research: Used as a reference standard or probe in studies investigating steroid receptor interactions and metabolic pathways.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex, biologically active steroidal compounds.
• Academic & Institutional Research: Employed in university and institutional labs for pharmacological and chemical research projects.
• Contract Development and Manufacturing (CDMO): Supplied to CDMOs for use in custom synthesis and process development for client projects.

Basic Information

Product Name	(20R)-3α-[(5,5-Dimethyl-3-Oxo-1-Cyclohexen-1-Yl)Amino]-20-Hydroxypregn-5-En-18-Oic Acid γ-Lactone
CAS No.	55401-43-9
Molecular Formula	C30H43NO4
Molecular Weight	481.67 g/mol
Synonyms	20-Hydroxy-3α-[(5,5-dimethyl-3-oxo-1-cyclohexen-1-yl)amino]pregn-5-en-18-oic acid γ-lactone; 3α-[(5,5-Dimethyl-3-oxo-1-cyclohexen-1-yl)amino]-20-hydroxypregn-5-en-18-oic acid γ-lactone; (20R)-3α-[(5,5-Dimethyl-3-oxo-1-cyclohexen-1-yl)amino]-20-hydroxypregn-5-en-18-oic acid γ-lactone; Canrenone derivative; Steroidal γ-lactone intermediate; Pregn-5-ene-18-oic acid, 3α-[(5,5-dimethyl-3-oxo-1-cyclohexen-1-yl)amino]-20-hydroxy-, γ-lactone, (20R)-
EINECS	Contact for details

Quality Control

Our (20R)-3α-[(5,5-Dimethyl-3-Oxo-1-Cyclohexen-1-Yl)Amino]-20-Hydroxypregn-5-En-18-Oic Acid γ-Lactone is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.