Description

20-[(1-Methylethylidene)Amino]Pregnan-18-Ol is a high-purity steroidal amine derivative, serving as a critical advanced intermediate in pharmaceutical synthesis. Its value lies in providing a versatile and reactive scaffold for the development of novel therapeutic agents, particularly within the field of endocrinology. This compound is essential for research institutions and pharmaceutical manufacturers focused on creating next-generation steroid-based drugs and hormone modulators.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroidal drugs and hormone therapies.
• Research & Development: Used in academic and industrial R&D for studying steroid receptor interactions and metabolic pathways.
• Endocrine System Modulators: Precursor in the development of compounds targeting adrenal and gonadal hormone functions.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for complex steroid molecules.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	20-[(1-Methylethylidene)Amino]Pregnan-18-Ol
CAS No.	55400-12-9
Molecular Formula	C24H41NO
Molecular Weight	359.59 g/mol
Synonyms	20-Isopropylideneaminopregnan-18-ol; 18-Hydroxy-20-isopropylidenaminopregnane; Pregnan-18-ol, 20-[(1-methylethylidene)amino]-; 20-(Isopropylideneamino)pregnan-18-ol; 20-Deoxydihydrocortisone isopropylidene derivative (related); Steroidal amine intermediate 55400-12-9
EINECS	Contact for details

Quality Control

Every batch of 20-[(1-Methylethylidene)Amino]Pregnan-18-Ol is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC and spectroscopic methods, to ensure compliance with high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.