Description

3-[Methyl(Trifluoroacetyl)Amino]Propionic Acid (S)-1-Methylpropyl Ester is a specialized chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for constructing complex molecules with defined stereochemistry, particularly in the pharmaceutical sector. This compound is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the multi-step synthesis of novel therapeutic agents, particularly for introducing specific stereocenters.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides, where biological activity is often stereospecific.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to produce high-value, single-enantiomer compounds.
• Peptidomimetics & Prodrug Development: Employed in the design and synthesis of peptide analogs and prodrug formulations to enhance bioavailability and metabolic stability.
• Ligand & Catalyst Preparation: Useful for synthesizing specialized chiral ligands and organocatalysts used in stereoselective transformations.
• Academic & Industrial R&D: A valuable reagent for methodological studies in synthetic organic chemistry within university and corporate research laboratories.

Basic Information

Product Name	3-[Methyl(Trifluoroacetyl)Amino]Propionic Acid (S)-1-Methylpropyl Ester
CAS No.	54986-71-9
Molecular Formula	C10H14F3NO3
Molecular Weight	253.22 g/mol
Synonyms	(S)-1-Methylpropyl 3-[Methyl(trifluoroacetyl)amino]propanoate; (S)-sec-Butyl 3-[Methyl(trifluoroacetamido)]propionate; N-Methyl-N-(trifluoroacetyl)-β-alanine (S)-sec-Butyl Ester; 3-[(Methyl)(trifluoroacetyl)amino]propanoic Acid (2S)-butan-2-yl Ester; (S)-sec-Butyl 3-(Methyl(trifluoroacetyl)amino)propionate; β-Alanine, N-methyl-N-(trifluoroacetyl)-, (S)-sec-butyl ester; (S)-2-Butyl 3-(Methyl(trifluoroacetamido))propanoate
EINECS	Contact for details

Quality Control

Our production of 3-[Methyl(Trifluoroacetyl)Amino]Propionic Acid (S)-1-Methylpropyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity, essential for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and GC-MS to confirm identity, enantiomeric excess, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.