Description

Nadoxolol CAS NO 54063-51-3 is a synthetic organic compound belonging to the chemical class of β-adrenergic blocking agents (β-blockers). This compound is of significant interest in pharmaceutical research and development for its potential pharmacological activity. It serves as a crucial intermediate or active pharmaceutical ingredient (API) for the synthesis of novel therapeutic agents targeting cardiovascular conditions. Industries involved in fine chemical synthesis, generic drug manufacturing, and advanced pharmaceutical R&D require high-purity Nadoxolol to ensure the efficacy and safety of their final products.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of β-blocker APIs and related cardiovascular drugs.
• Research & Development: Serves as a reference standard or starting material in medicinal chemistry for developing new adrenergic receptor antagonists.
• Generic Drug Manufacturing: Used in the production of generic versions of β-adrenergic blocking medications.
• Biochemical Research: Employed in pharmacological studies to investigate β-adrenergic receptor mechanisms and functions.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for specialized organic molecules.

Basic Information

Product Name	Nadoxolol
CAS No.	54063-51-3
Molecular Formula	C17H27NO4
Molecular Weight	309.40 g/mol
Synonyms	Nadoxolol; 54063-51-3; 1-(tert-Butylamino)-3-[(5,6,7,8-tetrahydro-cis-6,7-dihydroxy-1-naphthyl)oxy]-2-propanol; (RS)-Nadoxolol; DL-Nadoxolol; (±)-Nadoxolol; BRN 3911794; UNII-6E3K6W3THQ
EINECS	Contact for details

Quality Control

Our Nadoxolol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) that detail specifications such as assay, related substances, and residual solvents, compliant with relevant ICH guidelines. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical development and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.