Description

Clobetasone is a potent synthetic corticosteroid belonging to the glucocorticoid class, widely recognized for its anti-inflammatory and immunosuppressive properties. Its primary commercial value lies in its critical role as a key pharmaceutical intermediate in the synthesis of topical corticosteroid medications. This compound is essential for manufacturers in the pharmaceutical industry, particularly those developing dermatological treatments for conditions such as eczema, psoriasis, and other inflammatory skin disorders.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of topical corticosteroid drugs like Clobetasone Butyrate.
• Dermatological Preparations: Used in the manufacture of creams, ointments, and lotions for treating inflammatory skin conditions.
• Anti-inflammatory Agent Production: Serves as a precursor for other potent glucocorticoid agents used in various therapeutic areas.
• Research & Development: Utilized in pharmaceutical R&D for studying corticosteroid activity and developing new drug formulations.
• Veterinary Medicine: Applied in the development of anti-inflammatory treatments for animals.

Basic Information

Product Name	Clobetasone
CAS No.	54063-32-0
Molecular Formula	C22H28ClFO4
Molecular Weight	410.91 g/mol
Synonyms	Clobetasone; 21-Chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione; Clobetasone base; 21-Chloro-9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione; NSC-134455; (11β,16β)-21-Chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
EINECS	Contact for details

Quality Control

Our Clobetasone is produced under strict quality management systems to ensure it meets the high-purity standards required for pharmaceutical synthesis. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.