Description

Buserilin is a synthetic nonapeptide analog of the natural gonadotropin-releasing hormone (GnRH). This compound is a potent agonist of the GnRH receptor, making it a critical active pharmaceutical ingredient (API) for therapeutic applications. It is primarily utilized in the pharmaceutical and advanced life science research sectors. Buserilin CAS NO 54060-47-8 is essential for developing treatments in endocrinology and oncology.

Application

• Pharmaceutical API: Core ingredient in injectable formulations for the treatment of hormone-dependent conditions such as prostate cancer, endometriosis, and central precocious puberty.
• Hormone Therapy: Used in controlled ovarian stimulation protocols as part of assisted reproductive technology (ART) and in-vitro fertilization (IVF).
• Advanced Research: Serves as a key reference standard and tool compound in pharmacological studies of the hypothalamic-pituitary-gonadal axis.
• Veterinary Medicine: Applied in fertility control and the treatment of reproductive disorders in animals.
• Drug Development: Used in the R&D of novel GnRH agonist and antagonist therapies and in pharmacokinetic studies.

Basic Information

Product Name	Buserilin
CAS No.	54060-47-8
Molecular Formula	C60H86N16O13
Molecular Weight	1239.4 g/mol
Synonyms	Buserelin; Buserelin Acetate; D-Ser(But)6,Azgly10-LHRH; Hoe 766; Salk Institute LHRH Agonist; Receptal; Suprefact; Gonadorelin (6-D-Ser-tert-butyl-10-aza-glycinamide); [6-O-tert-Butyl-D-serine,10-aza-glycine]gonadorelin
EINECS	Contact for details

Quality Control

Our Buserilin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, peptide content determination, and identity confirmation via mass spectrometry. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with cGMP and relevant pharmacopeial guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccated environment after opening to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Bacterial Endotoxins	< 10.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.