Description

(D-Leu7)-Lhrh is a synthetic peptide analog of the gonadotropin-releasing hormone (GnRH). This compound is of significant interest in biochemical and pharmaceutical research due to its modified structure, which confers specific receptor binding and biological activity profiles. It is primarily utilized by research institutions and pharmaceutical developers in the fields of endocrinology, oncology, and reproductive medicine for advanced studies and potential therapeutic applications.

Application

• Biochemical Research: Used as a reference standard and tool compound for studying GnRH receptor mechanisms and signaling pathways.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of novel hormone-based therapeutics.
• Endocrinology Studies: Applied in in vitro and in vivo models to investigate the regulation of the hypothalamic-pituitary-gonadal axis.
• Oncology Research: Explored for its potential role in hormone-dependent cancers and as a targeting moiety for drug delivery systems.
• Veterinary Medicine: Potential applications in animal reproductive health management and fertility control studies.

Basic Information

Product Name	(D-Leu7)-Lhrh
CAS No.	53728-75-9
Molecular Formula	C59H83N17O13
Molecular Weight	1214.4 g/mol
Synonyms	(Des-Gly10, D-Leu6, Pro9-NHEt)-LHRH; (D-Leu6, Pro9-NHEt)-LHRH; AY-25,205; Des-Gly10-(D-Leu6)-LHRH ethylamide; Fertirelin acetate; Gonadorelin (6-D-leucine, 9-(N-ethyl-L-prolinamide), 10-deglycinamide); LHRH, (D-Leu6, des-Gly10)-, ethylamide; P-Glu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt
EINECS	Contact for details

Quality Control

Our (D-Leu7)-Lhrh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Water Content (KF)	≤ 5.0%
Peptide Content (N)	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.