Description

Methanesulfonamide, n-(2-Cyanophenyl)-1,1,1-Trifluoro- is a specialized trifluoromethylated sulfonamide derivative, valued for its unique combination of structural motifs. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily sought by R&D and production teams in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Building block for novel herbicides and fungicides, leveraging the trifluoromethyl group for enhanced biological activity and environmental stability.
• Material Science Research: Used in the development of specialty polymers and advanced organic electronic materials due to its electron-withdrawing properties.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands in asymmetric catalysis and transition metal complexes.
• Fluorine Chemistry Studies: A valuable compound for research into the effects of fluorination on molecular properties and reactivity.

Basic Information

Product Name	Methanesulfonamide, n-(2-Cyanophenyl)-1,1,1-Trifluoro-
CAS No.	53718-42-6
Molecular Formula	C9H5F3N2O2S
Molecular Weight	262.21 g/mol
Synonyms	N-(2-Cyanophenyl)-1,1,1-trifluoromethanesulfonamide; 1,1,1-Trifluoro-N-(2-cyanophenyl)methanesulfonamide; 2-Cyano-N-(trifluoromethylsulfonyl)aniline; α,α,α-Trifluoro-N-(2-cyanophenyl)methanesulfonamide; Trifluoromethanesulfonanilide, 2-cyano-; 2-Cyanophenyl trifluoromethanesulfonamide
EINECS	Contact for details

Quality Control

Our production of Methanesulfonamide, n-(2-Cyanophenyl)-1,1,1-Trifluoro- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We support cGMP and ISO 9001 compliant manufacturing for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.